Bactrim DS Uses, Side Effects & Warnings - bookswelove.net

Skipping doses can increase your risk of infection that is resistant to medication. This medicine will not treat a viral infection such as the flu or a common cold.

You may need frequent medical tests. This medicine can affect the results of certain medical tests. Tell any doctor who treats you that you are using sulfamethoxazole and trimethoprim. Store at room temperature away from moisture, heat, and light. What happens if I miss a dose? Use the medicine as soon as you can, but skip the missed dose if it is almost time for your next dose.

Do not use two doses at one time. What happens if I overdose? Seek emergency medical attention or call the Poison Help line at Overdose symptoms may include loss of appetite, vomiting , fever, blood in your urine, yellowing of your skin or eyes, confusion, or loss of consciousness. What should I avoid while using Bactrim DS? Antibiotic medicines can cause diarrhea , which may be a sign of a new infection. If you have diarrhea that is watery or bloody, call your doctor before using anti-diarrhea medicine.

Bactrim DS could make you sunburn more easily. Avoid sunlight or tanning beds. Antibiotic medicines can cause diarrhea , which may be a sign of a new infection.

If you have diarrhea that is watery or bloody, call your doctor before using anti-diarrhea medicine. Bactrim could make you sunburn more easily.

Avoid sunlight or tanning beds. Wear protective clothing and use sunscreen SPF 30 or higher when you are outdoors. Bactrim side effects Get emergency medical help if you have signs of an allergic reaction to Bactrim hives , cough, shortness of breath, swelling in your face or throat or a severe skin reaction fever, sore throat , burning eyes, skin pain, red or purple skin rash with blistering and peeling.

Call your doctor at once if you have: severe stomach pain, diarrhea that is watery or bloody even if it occurs months after your last dose ; a skin rash, no matter how mild; yellowing of your skin or eyes; a seizure; new or unusual joint pain; increased or decreased urination; swelling, bruising, or irritation around the IV needle; increased thirst, dry mouth, fruity breath odor; an electrolyte imbalance - headache , confusion, weakness, slurred speech, tingly feeling, chest pain, irregular heartbeats, loss of coordination or movement, feeling unsteady, vomiting; or low blood cell counts - fever, chills, mouth sores, skin sores, easy bruising, unusual bleeding, pale skin, cold hands and feet, feeling light-headed or short of breath.

Common Bactrim side effects may include: nausea , vomiting, loss of appetite; or skin rash. This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. Bactrim side effects more detail What other drugs will affect Bactrim? This combination of antibiotics, according to Medline Plus, a website of the National Institutes of Health, is often given for infections of the ears, urinary tract, intestines and lungs 3.

Patients may also experience swelling of the face, lips and tongue and may develop trouble breathing or swallowing as a result of the airway swelling. Some patients may also develop hoarseness. In extreme cases, the airway may close entirely which is a medical emergency. An allergic reaction to Bactrim DS often manifests itself as itching, hives or a rash, Drugs. With Stevens-Johnson syndrome, patients develop a fever, headache and general fatigue as well as characteristic red bumps on their skin 2.

Does bactrim make you sleepy or tired more ? | Yahoo Answers

Symptoms may include: side rash, fever, swollen glands, muscle aches, severe weakness, unusual bruising, or sleepy of your skin or eyes. Do not use in larger or smaller amounts or for longer than recommended.

Drink effects of fluids to prevent kidney stones while clinic are using this medicine. The antibacterial effects of Bactrim persist for at least 12 hours. A healthcare provider will give the first injection and may teach you how to properly use the medication by yourself.

This medicine can affect the results of certain medical tests. Common medications that may interact with Bactrim include: anticonvulsants visit the website as phenytoin antidepressants, such as amitriptyline, amoxapine, and desipramine cyclosporine anticoagulants blood thinnerssuch as warfarin blood bactrim medications, such as captopril or enalapril indomethacin medications that affect the nervous system, such as amantadine or memantine methotrexate.

If you have diarrhea that is watery or bloody, call your doctor before using anti-diarrhea medicine. May interact mayo a number of other drugs bactrim thiazides, warfarin, phenytoin, leucovorin, methotrexate, digoxin, and medications for diabetes.

Does bactrim make you sleepy or tired more ?

Not suitable for pregnant or breastfeeding women or in infants less than two months of age. Use effective birth control, and tell your doctor if you become pregnant.

Sulfamethoxazole and trimethoprim doses are comes on weight in bactrim. This medicine is taken by mouth oral or given as an learn more into what vein injection. The antibacterial effects of Bactrim persist for at least 12 hours.

Do not use two doses at one time. Sulfamethoxazole and trimethoprim doses are based on weight in children.

Bactrim (Sulfamethoxazole and Trimethoprim Oral/Injection)

Do not use two doses at one time. If you have diarrhea that is watery or bloody, call your doctor before using anti-diarrhea medicine.

This is not a complete info of sleepy effects and others may occur. Wear protective clothing and use sunscreen Bactrim 30 or higher when you are outdoors. Call your doctor for medical advice about side effects. Like other antibiotics, Bactrim can change the natural balance of bacteria present in your gut and may cause severe and persistent diarrhea, associated with a bacteria called Clostridium difficile.

Bactrim: 7 things you should know

Effects the oral suspension liquid before you measure a dose. Bactrim clinic to the class bactrim medicines known as antibiotics. Call your doctor at once if you have: severe stomach pain, diarrhea that is watery or bloody even if it occurs months after your last dose ; a skin rash, no matter how mild; yellowing of your skin or eyes; bactrim seizure; new or unusual joint pain; increased mayo decreased urination; swelling, bruising, or irritation around the IV needle; increased thirst, dry mouth, fruity breath odor; an electrolyte imbalance - headacheconfusion, paroxetine 20mg tablets reviews, slurred sleepy, tingly feeling, chest pain, irregular heartbeats, loss of coordination or movement, feeling unsteady, vomiting; or low blood cell counts - fever, chills, mouth sores, skin sores, easy bruising, unusual bleeding, pale skin, cold hands and feet, feeling light-headed or short of side.

Follow all directions on your prescription label and read all medication guides or instruction sheets.

Bactrim side to the class of medicines known as antibiotics. Store at room temperature away clinic moisture, heat, and light. Get bactrim medical help if you have signs of an allergic effects hives, cough, shortness of breath, swelling in mayo face or throat or a severe skin reaction fever, sore throat, burning eyes, skin pain, red or purple skin rash with blistering and peeling.

May lower blood sugar levels in people without mayo. Effective concentrations of side sulfamethoxazole and trimethoprim are reached in the gastrointestinal tract, urinary tract, lungs, mouth, middle ear, and vagina. The risk of side effects may be higher in the elderly.

Seek medical treatment if you have a serious drug reaction that can affect bactrim parts of your body. Rarely, severe, clinic fatal reactions have been reported following the administration of sulfonamide-containing medicines such as Bactrim.

Do not use in larger or smaller effects or for longer than recommended. Bactrim side effects more detail What other drugs will affect Bactrim? This medicine could harm the unborn baby or cause birth defects.

Use only the recommended dose when giving this medicine to a child. This is not a bactrim list of side effects and others may occur. Bactrim side effects Get emergency medical help if you have signs of side allergic reaction to Effects hivescough, shortness of breath, swelling in your face or throat sleepy a severe skin reaction fever, sore throatburning eyes, skin pain, red or purple skin rash with blistering and peeling. Use mayo dosing syringe provided, clinic use a medicine dose-measuring device not a kitchen spoon.

Follow site directions on your prescription label and read all medication guides or instruction sheets.

Store at room temperature away from moisture, heat, and light. Bactrim plenty of fluids to prevent kidney stones while you are using this medicine. Use effective birth control, and tell your doctor if you continue pregnant.

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Note: In general, seniors or children, people with certain medical conditions such as liver or kidney problems, heart disease, diabetes, seizures or people who take other medications are more at risk of developing a wider range of side effects. View complete list of side effects 4. Bottom Line Bactrim is an effective combination antibiotic; however, it may not be suitable for those with kidney or liver disease or folate deficiency. The risk of side effects may be higher in the elderly.

Tips May be taken with or without food. Swallow tablets with a big glass of water. Take only as directed by your doctor and do not share with anyone else as misuse can encourage the development of drug-resistant bacteria and reduce the effectiveness of Bactrim.

Bactrim will not treat viral infections, such as a cold, or some bacterial infections such as those caused by streptococcal bacteria. Discontinue and seek urgent medical advice if a skin rash develops. Complete the full course as prescribed unless instructed not to do so by your doctor to reduce the risk of resistant bacteria developing. Should not be used in pregnant or lactating women or in babies less than two months old.

Seek urgent medical advice if an unexplained cough, shortness of breath, sore throat, fever, muscle or joint pain, paleness or yellowing of the skin, or diarrhea develop. Like other antibiotics, Bactrim can change the natural balance of bacteria present in your gut and may cause severe and persistent diarrhea, associated with a bacteria called Clostridium difficile.

Ask your doctor or pharmacist if you don't understand all instructions. Drink plenty of fluids to prevent kidney stones while you are using this medicine. Sulfamethoxazole and trimethoprim doses are based on weight in children. Use only the recommended dose when giving this medicine to a child. Use this medicine for the full prescribed length of time, even if your symptoms quickly improve. Skipping doses can increase your risk of infection that is resistant to medication. This medicine will not treat a viral infection such as the flu or a common cold.

You may need frequent medical tests. This medicine can affect the results of certain medical tests. Tell any doctor who treats you that you are using sulfamethoxazole and trimethoprim. Store at room temperature away from moisture, heat, and light. Use the medicine as soon as you can, but skip the missed dose if it is almost time for your next dose.

Do not use two doses at one time. If you have diarrhea that is watery or bloody, call your doctor before using anti-diarrhea medicine. Bactrim could make you sunburn more easily. Avoid sunlight or tanning beds. Wear protective clothing and use sunscreen SPF 30 or higher when you are outdoors.

Bactrim side effects Get emergency medical help if you have signs of an allergic reaction to Bactrim hives , cough, shortness of breath, swelling in your face or throat or a severe skin reaction fever, sore throat , burning eyes, skin pain, red or purple skin rash with blistering and peeling.

Seek medical treatment if you have a serious drug reaction that can affect many parts of your body. Symptoms may include: skin rash, fever, swollen glands, muscle aches, severe weakness, unusual bruising, or yellowing of your skin or eyes. Call your doctor at once if you have: severe stomach pain, diarrhea that is watery or bloody even if it occurs months after your last dose ; a skin rash, no matter how mild; yellowing of your skin or eyes; a seizure; new or unusual joint pain; increased or decreased urination; swelling, bruising, or irritation around the IV needle; increased thirst, dry mouth, fruity breath odor; an electrolyte imbalance - headache , confusion, weakness, slurred speech, tingly feeling, chest pain, irregular heartbeats, loss of coordination or movement, feeling unsteady, vomiting; or low blood cell counts - fever, chills, mouth sores, skin sores, easy bruising, unusual bleeding, pale skin, cold hands and feet, feeling light-headed or short of breath.

Common Bactrim side effects may include: nausea , vomiting, loss of appetite; or skin rash. This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. Bactrim side effects more detail What other drugs will affect Bactrim? You may need more frequent check- ups or medical tests if you also use medicine to treat depression , diabetes, seizures , or HIV.

Side effects may include flushing, sweating, nausea, vomiting, difficulty breathing, or pain at the injection site. But larger amounts given by IV are POSSIBLY UNSAFE.

Bactrim - FDA prescribing information, side effects and uses

Sulfamethoxazole / Trimethoprim | ClinicalInfo
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Bactrim Description

When culture and susceptibility information are available, they should be considered in selecting or modifying antibacterial therapy. Clinic history mayo mild intolerance to Bactrim in AIDS patients does not appear to predict intolerance of subsequent secondary prophylaxis.

Bactrim is also contraindicated in patients with marked hepatic damage or with severe renal insufficiency when renal function status cannot be monitored. Clostridioides difficile associated diarrhea Clostridioides difficile associated diarrhea CDAD has been reported with use of nearly all antibacterial agents, here Bactrim, effects may range in severity from mild diarrhea to bactrim colitis.

Pneumocystis jirovecii Pneumonia: For the treatment of documented Pneumocystis jirovecii pneumonia and for prophylaxis against Side. The trimethoprim component of BACTRIM may cause hyperkalemia when administered to patients with underlying disorders of potassium this web, with renal insufficiency or when given sleepy with drugs known to induce hyperkalemia, such as angiotensin converting enzyme bactrim.

Traveler's Diarrhea in Adults: For the treatment of traveler's diarrhea due to susceptible strains of enterotoxigenic E.

Pneumocystis jirovecii Pneumonia: For the treatment of documented Pneumocystis jirovecii pneumonia and for prophylaxis against P.

Severe cases of thrombocytopenia that are fatal or life threatening have been reported. Bactrim studies, however, were limited by the small number of exposed cases and the lack of adjustment for multiple statistical comparisons comes confounders.

The usual dose is 40 milligrams mg per kilogram of body Blog of sulfamethoxazole and 8 milligrams mg per kilogram of body weight of trimethoprim, what in two divided doses every 12 hours for 10 days.

For treatment of Pneumocystis jiroveci pneumonia or Pneumocystis carinii pneumonia PCP : Adults and children 2 months of age and older—Dose is based on body weight and must be determined by your doctor. In an established infection, they will not eradicate the streptococcus and, therefore, will not prevent sequelae such as rheumatic fever.

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Diagnosed nine months ago with MAC and bronchiectasis. Taking azithromycin, ethambutol and rifampin. In the last two months have developed severe itching of arms and legs, which pulmonologist does not attribute to meds. Neither dermatologist- prescribed creams or change of bath soap, lotions and laundry detergent have helped. I am [ ].

In an established infection, they will not eradicate the streptococcus and, therefore, will not prevent sequelae such as rheumatic fever. Clostridioides difficile associated diarrhea Clostridioides difficile associated diarrhea CDAD has been reported with use of nearly all antibacterial agents, including BACTRIM, and may range in severity from mild diarrhea to fatal colitis.

Treatment with antibacterial agents alters the normal flora of the colon leading to overgrowth of C. Hypertoxin producing strains of C. CDAD must be considered in all patients who present with diarrhea following antibiotic use. Careful medical history is necessary since CDAD has been reported to occur over two months after the administration of antibacterial agents.

Appropriate fluid and electrolyte management, protein supplementation, antibiotic treatment of C. Adjunctive treatment with Leucovorin for Pneumocystis jirovecii pneumonia Treatment failure and excess mortality were observed when trimethoprim-sulfamethoxazole was used concomitantly with leucovorin for the treatment of HIV positive patients with Pneumocystis jirovecii pneumonia in a randomized placebo controlled trial.

Folate deficiency BACTRIM should be given with caution to patients with impaired renal or hepatic function, to those with possible folate deficiency e. Hematological changes indicative of folic acid deficiency may occur in elderly patients or in patients with preexisting folic acid deficiency or kidney failure.

These effects are reversible by folinic acid therapy. Hemolysis In glucosephosphate dehydrogenase deficient individuals, hemolysis may occur. Phenylalanine metabolism Trimethoprim has been noted to impair phenylalanine metabolism, but this is of no significance in phenylketonuric patients on appropriate dietary restriction. Porphyria and Hypothyroidism As with all drugs containing sulfonamides, caution is advisable in patients with porphyria or thyroid dysfunction.

Electrolyte Abnormalities High dosage of trimethoprim, as used in patients with P. Even treatment with recommended doses may cause hyperkalemia when trimethoprim is administered to patients with underlying disorders of potassium metabolism, with renal insufficiency, or if drugs known to induce hyperkalemia are given concomitantly.

Close monitoring of serum potassium is warranted in these patients. Evaluation for hyponatremia and appropriate correction is necessary in symptomatic patients to prevent life-threatening complications. During treatment, adequate fluid intake and urinary output should be ensured to prevent crystalluria. Information for Patients: Patients should be counseled that antibacterial drugs including Bactrim sulfamethoxazole and trimethoprim tablets should only be used to treat bacterial infections.

They do not treat viral infections e. When Bactrim sulfamethoxazole and trimethoprim tablets are prescribed to treat a bacterial infection, patients should be told that although it is common to feel better early in the course of therapy, the medication should be taken exactly as directed.

Skipping doses or not completing the full course of therapy may 1 decrease the effectiveness of the immediate treatment and 2 increase the likelihood that bacteria will develop resistance and will not be treatable by Bactrim sulfamethoxazole and trimethoprim tablets or other antibacterial drugs in the future.

Patients should be instructed to maintain an adequate fluid intake in order to prevent crystalluria and stone formation. Diarrhea is a common problem caused by antibiotics which usually ends when the antibiotic is discontinued. Sometimes after starting treatment with antibiotics, patients can develop watery and bloody stools with or without stomach cramps and fever even as late as two or more months after having taken the last dose of the antibiotic. If this occurs, patients should contact their physician as soon as possible.

Urinalyses with careful microscopic examination and renal function tests should be performed during therapy, particularly for those patients with impaired renal function. Sulfamethoxazole is an inhibitor of CYP2C9. In elderly patients concurrently receiving certain diuretics, primarily thiazides, an increased incidence of thrombocytopenia with purpura has been reported.

This interaction should be kept in mind when BACTRIM is given to patients already on anticoagulant therapy, and the coagulation time should be reassessed. When administering these drugs concurrently, one should be alert for possible excessive phenytoin effect.

Sulfonamides can also displace methotrexate from plasma protein binding sites and can compete with the renal transport of methotrexate, thus increasing free methotrexate concentrations. There have been reports of marked but reversible nephrotoxicity with coadministration of BACTRIM and cyclosporine in renal transplant recipients.

Serum digoxin levels should be monitored. Increased sulfamethoxazole blood levels may occur in patients who are also receiving indomethacin. Occasional reports suggest that patients receiving pyrimethamine as malaria prophylaxis in doses exceeding 25 mg weekly may develop megaloblastic anemia if BACTRIM is prescribed.

Additional monitoring of blood glucose may be warranted. Cases of interactions with other OCT2 substrates, memantine and metformin, have also been reported. No interference occurs, however, if methotrexate is measured by a radioimmunoassay RIA. Mutagenesis: In vitro reverse mutation bacterial tests according to the standard protocol have not been performed with sulfamethoxazole and trimethoprim in combination. Observations of leukocytes obtained from patients treated with sulfamethoxazole and trimethoprim revealed no chromosomal abnormalities.

Sulfamethoxazole alone was positive in an in vitro reverse mutation bacterial assay and in in vitro micronucleus assays using cultured human lymphocytes. Trimethoprim alone was negative in in vitro reverse mutation bacterial assays and in in vitro chromosomal aberration assays with Chinese Hamster ovary or lung cells with or without S9 activation.

In in vitro Comet, micronucleus and chromosomal damage assays using cultured human lymphocytes, trimethoprim was positive. In mice following oral administration of trimethoprim, no DNA damage in Comet assays of liver, kidney, lung, spleen, or bone marrow was recorded. Co-administration of Bactrim and leucovorin should be avoided with P. Electrolyte Abnormalities High dosage of trimethoprim, as used in patients with P. Even treatment with recommended doses may cause hyperkalemia when trimethoprim is administered to patients with underlying disorders of potassium metabolism, with renal insufficiency, or if drugs known to induce hyperkalemia are given concomitantly.

Close monitoring of serum potassium is warranted in these patients. Severe and symptomatic hyponatremia can occur in patients receiving Bactrim, particularly for the treatment of P. Evaluation for hyponatremia and appropriate correction is necessary in symptomatic patients to prevent life-threatening complications. During treatment, adequate fluid intake and urinary output should be ensured to prevent crystalluria.

Information for Patients: Patients should be counseled that antibacterial drugs including Bactrim sulfamethoxazole and trimethoprim tablets should only be used to treat bacterial infections. They do not treat viral infections e. When Bactrim sulfamethoxazole and trimethoprim tablets are prescribed to treat a bacterial infection, patients should be told that although it is common to feel better early in the course of therapy, the medication should be taken exactly as directed.

Sometimes after starting treatment with antibiotics, patients can develop watery and bloody stools with or without stomach cramps and fever even as late as two or more months after having taken the last dose of the antibiotic.

If this occurs, patients should contact their physician as soon as possible. Laboratory Tests: Complete blood counts should be done frequently in patients receiving Bactrim; if a significant reduction in the count of any formed blood element is noted, Bactrim should be discontinued.

It has been reported that Bactrim may prolong the prothrombin time in patients who are receiving the anticoagulant warfarin a CYP2C9 substrate.

This interaction should be kept in mind when Bactrim is given to patients already on anticoagulant therapy, and the coagulation time should be reassessed. Bactrim may inhibit the hepatic metabolism of phenytoin a CYP2C9 substrate. When administering these drugs concurrently, one should be alert for possible excessive phenytoin effect. Sulfonamides can also displace methotrexate from plasma protein binding sites and can compete with the renal transport of methotrexate, thus increasing free methotrexate concentrations.

There have been reports of marked but reversible nephrotoxicity with coadministration of Bactrim and cyclosporine in renal transplant recipients. Increased digoxin blood levels can occur with concomitant Bactrim therapy, especially in elderly patients.

Bactrim potentiates the effect of oral hypoglycemics that are metabolized by CYP2C8 e. Additional monitoring of blood glucose may be warranted. Cases of interactions with other OCT2 substrates, memantine and metformin, have also been reported. No interference occurs, however, if methotrexate is measured by a radioimmunoassay RIA.

Mutagenesis: In vitro reverse mutation bacterial tests according to the standard protocol have not been performed with sulfamethoxazole and trimethoprim in combination. Observations of leukocytes obtained from patients treated with sulfamethoxazole and trimethoprim revealed no chromosomal abnormalities.

In mice following oral administration of trimethoprim, no DNA damage in Comet assays of liver, kidney, lung, spleen, or bone marrow was recorded. Pregnancy: While there are no large, well-controlled studies on the use of sulfamethoxazole and trimethoprim in pregnant women, Brumfitt and Pursell,8 in a retrospective study, reported the outcome of pregnancies during which the mother received either placebo or sulfamethoxazole and trimethoprim.

The incidence of congenital abnormalities was 4. There were no abnormalities in the 10 children whose mothers received the drug during the first trimester. In a separate survey, Brumfitt and Pursell also found no congenital abnormalities in 35 children whose mothers had received oral sulfamethoxazole and trimethoprim at the time of conception or shortly thereafter. Because sulfamethoxazole and trimethoprim may interfere with folic acid metabolism, Bactrim should be used during pregnancy only if the potential benefit justifies the potential risk to the fetus.

These studies, however, were limited by the small number of exposed cases and the lack of adjustment for multiple statistical comparisons and confounders. These studies are further limited by recall, selection, and information biases, and by limited generalizability of their findings.

Lastly, outcome measures varied between studies, limiting cross-study comparisons. These doses are approximately 5 and 6 times the recommended human total daily dose on a body surface area basis. In some rabbit studies, an overall increase in fetal loss dead and resorbed conceptuses was associated with doses of trimethoprim 6 times the human therapeutic dose based on body surface area.

Caution should be exercised when Bactrim is administered to a nursing woman, especially when breastfeeding, jaundiced, ill, stressed, or premature infants because of the potential risk of bilirubin displacement and kernicterus. Geriatric Use: Clinical studies of Bactrim did not include sufficient numbers of subjects aged 65 and over to determine whether they respond differently from younger subjects.

There may be an increased risk of severe adverse reactions in elderly patients, particularly when complicating conditions exist, e. In those concurrently receiving certain diuretics, primarily thiazides, an increased incidence of thrombocytopenia with purpura has been reported.

Hematological changes indicative of folic acid deficiency may occur in elderly patients. The trimethoprim component of Bactrim may cause hyperkalemia when administered to patients with underlying disorders of potassium metabolism, with renal insufficiency or when given concomitantly with drugs known to induce hyperkalemia, such as angiotensin converting enzyme inhibitors.

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